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Mandi Murph, Ph.D.
Assistant Professor
Pharmaceutical and Biomedical Sciences
Office: Room 376, R.C. Wilson Pharmacy Building
Phone: (706) 583-0216
E-mail: mmurph@rx.uga.edu
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Biosketch
| B.S. Biology | Emory University | Atlanta, GA | 1999 | | Ph.D., Biology | Georgia Institute of Technology | Atlanta, GA | 2005 |
Post-doctoral Experience M.D. Anderson Cancer Center, Postdoctoral Fellow, Houston, TX, 2005-2008 Representative Publications Yu, S.*, Murph M.M.*, Lu, Y.,Liu, S., Hall, H.S., Liu, J., Stephens, L.C., Fang, X., Mills, G.B.. (*2008*) Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells. J Natl Cancer Inst. Nov 19;100(22):1630-42.
Murph M.M, Nguyen, G.H., Radhakrishna, H. and Mills, GB. (*2008*) Sharpening the edges of understanding the structure/function of the LPA1 receptor: expression in cancer and mechanisms of regulation. Biochim Biophys Acta.. Sep;1781(9):547-557. PMID: 18501205
Hasegawa, Y.*, Murph, M.*, Yu, S., Tigyi, G. and.Mills, GB. (*2008*) Lysophosphatidic acid (LPA)-induced vasodilator-stimulated phosphoprotein mediates lamellipodia formation to initiate motility in PC-3 prostate cancer cells. Mol. Oncol. 2(1):54-69. PMID: 19081821
Murph, M., Tanaka, T., Pang, J., Felix, E., Trost, R., Liu, S., Newman, R., Mills, G.B. (*2007*) Liquid chromatography mass spectrometry for quantifying plasma lysophospholipids; potential biomarkers for cancer diagnosis. Methods Enzymol. 433:1-25. PMID:17954226.
Murph, M., Mills, G.B. (*2007*) Targeting the lipids LPA and S1P and their signaling pathways for inhibition of tumor progression. Expert Rev Mol Med. Oct 15;9(28):1-18. PMID: 17935635.
Murph M., Tanaka T., Liu S., Mills G.B. (*2006*). Of spiders and crabs: the emergence of lysophospholipids and their metabolic pathways as targets for therapy in cancer. Clin Cancer Res. 12(22):6598-602. PMID: 17121877.
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