UGA Pharmaceutical and Biomedical Sciences
 
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Faculty and Research

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Faculty: Biography

  Phillip Greenspan, Ph.D.
Associate Professor
Pharmaceutical and Biomedical Sciences

Office: Room 706, Boyd Graduate Studies
Phone: (706) 542-5410
E-mail: greenspn@rx.uga.edu

Biosketch
A.B (Cell Physiology)Rutgers CollegeNew Brunswick, New Jersey1973
Ph.D. (Pharmacology)University of IowaIowa City, Iowa1979
Postdoctoral Appt.NIH PD FellowBowman Gray School of Medicine1979-82
Research Assistant and Associate ProfessorUniv. South CarolinaColumbia, S.C.1982-91
Assistant ProfessorUniversity of GeorgiaAthens, GA1992-1997
Associate ProfessorUniversity of GeorgiaAthens, GA1997-Present

Research Interests
The cellular accumulation of cholesterol in atherogenesis
The role of oxidation of low density lipoprotein (LDL) in atherogenesis
The antioxidant and biological properties of specific drugs and natural products (nutraceuticals).

Representative Publications
T-M Chou and P. Greenspan, The Effect of Acetaminophen on the Myeloperoxidase-Hydrogen Peroxide-Nitrite Oxidation of LDL, Biochim. Biophys. Acta, 2002, 1581, 57-63.

B-H Ryu, J.W. Jeong , R.L. Gutman and P. Greenspan, Antioxidative Activity for Human Low Density Lipoprotein Oxidation by a Novel Compound Purified from Marine Microbial Origin, J. Marine Biotech., 1998, 6, 244-248.

H. Yu, R.L. Gutman , B-H Ryu and P. Greenspan, Cholesteryl Esterase-Treated LDL Augments Oxidized LDL-Mediated Cholesteryl Ester Deposition in Mouse Peritoneal Macrophages, Atherosclerosis, 1998, 140, 35- 43.

P. Greenspan, H. Yu , F. Mao and R.L. Gutman. Cholesterol Deposition in Macrophages: Foam Cell Formation Mediated by Cholesterol-Enriched Oxidized Low Density Lipoprotein, J. Lipid Res., 1997, 38, 101-109.