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Phillip Greenspan, Ph.D.
Associate Professor
Pharmaceutical and Biomedical Sciences
Office: Room 706, Boyd Graduate Studies
Phone: (706) 542-5410
E-mail: greenspn@rx.uga.edu
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Biosketch
| A.B (Cell Physiology) | Rutgers College | New Brunswick, New Jersey | 1973 | | Ph.D. (Pharmacology) | University of Iowa | Iowa City, Iowa | 1979 | | Postdoctoral Appt. | NIH PD Fellow | Bowman Gray School of Medicine | 1979-82 | | Research Assistant and Associate Professor | Univ. South Carolina | Columbia, S.C. | 1982-91 | | Assistant Professor | University of Georgia | Athens, GA | 1992-1997 | | Associate Professor | University of Georgia | Athens, GA | 1997-Present |
Research Interests The cellular accumulation of cholesterol in atherogenesis The role of oxidation of low density lipoprotein (LDL) in atherogenesis The antioxidant and biological properties of specific drugs and natural products (nutraceuticals).
Representative Publications T-M Chou and P. Greenspan, The Effect of Acetaminophen on the Myeloperoxidase-Hydrogen Peroxide-Nitrite Oxidation of LDL, Biochim. Biophys. Acta, 2002, 1581, 57-63.
B-H Ryu, J.W. Jeong , R.L. Gutman and P. Greenspan, Antioxidative Activity for Human Low Density Lipoprotein Oxidation by a Novel Compound Purified from Marine Microbial Origin, J. Marine Biotech., 1998, 6, 244-248.
H. Yu, R.L. Gutman , B-H Ryu and P. Greenspan, Cholesteryl Esterase-Treated LDL Augments Oxidized LDL-Mediated Cholesteryl Ester Deposition in Mouse Peritoneal Macrophages, Atherosclerosis, 1998, 140, 35- 43.
P. Greenspan, H. Yu , F. Mao and R.L. Gutman. Cholesterol Deposition in Macrophages: Foam Cell Formation Mediated by Cholesterol-Enriched Oxidized Low Density Lipoprotein, J. Lipid Res., 1997, 38, 101-109.
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