Recent Publications
2013
Mingming Gao and Dexi Liu (2013) The Liver X Receptor Agonist T0901317 Protects Mice from High Fat Diet Induced Obesity and Insulin Resistance. The AAPS J 15:258-266 (DOI:10.1208/s12248-012-9429-3).
Mingming Gao and Dexi Liu (2013) Resveratrol Suppresses T0901317-induced Hepatic Fat Accumulation in Mice. The AAPS J DOI:10.1208/s12248-012-9429-3.
Yongjie Ma, Yixian Huang, Linna Yan, Mingming Gao and Dexi Liu (2013) Synthetic FXR Agonist GW4064 Prevents Diet-induced Hepatic Steatosis and Insulin Resistance. Pharm Res DOI 10.1007/s11095-013-0986-7.
Yongjie Ma and Dexi Liu (2013) Hydrodynamic Delivery of Adiponectin and Adiponectin Receptor 2 Gene Blocks High-fat Diet-induced Obesity and Insulin Resistance. Gene Therapy doi:10.1038/gt.2013.8
T Yokoo, K Kamimura, T Suda, T Kanefuji, M Oda, G Zhang, D Liu and Y Aoyagi (2013) Novel Electric Power-driven Hydrodynamic Injection System for Gene Delivery: Safety and Efficacy of Human Factor IX Delivery in Rats. Gene Therapy doi:10.1038/gt.2013.2
Tremblay TP, Xiao X, Aartsma-Rus A et al (2013) Translating the Genomics Revolution: The Need for an International Gene Therapy Consortium for Monogenic Diseases. Molecular Therapy 21:266-268.
2012
Barbara Bonamassa, Yongjie Ma and Dexi Liu (2012) Glucocorticoid Receptor-mediated Transcriptional Regulation of N-acetyltransferase 1 Gene Through Distal Promoter. The AAPS J 14:581-590 (DOI:10.1208/s12248-012-9370-5).
Yongjie Ma and Dexi Liu (2012) Activation of Pregnane X Receptor by Pregnenolone 16 α carbonitrile Blocks High Fat-Diet Induced Obesity inAKR/J Mice. PLoS ONE 7(6): e38734. doi:10.1371/journal.pone.0038734.
A.C. McGinnis, B. Chen and M.G. Bartlett, “Chromatographic Methods for the Determination of Therapeutic Oligonucleotides.” Journal of Chromatography B, 883-884, 76-94 (2012).
A.V. Terry, J.J. Buccafusco, R. Schade, L. Vandenhuerk, P.M. Callahan, W.D. Beck, E.J. Hutchings, J.M. Chapman, P. Li and M.G. Bartlett, “The Nicotine Metabolite, Cotinine, Attenuates Glutamate (NMDA) Antagonist-related Effects on the Performance of the Five Choice Serial Reaction Time Task (5C-SRTT) in Rats.” Biochemical Pharmacology, 83, 941-951 (2012).
B. Chen and M.G. Bartlett, “Determination of Therapeutic Oligonucleotides Using Capillary Electrophoresis.” Biomedical Chromatography, 26, 409-418 (2012).
F. Liang, A.V. Terry and M.G. Bartlett, “Determination of Aripiprazole in Rat Plasma and Brain Using Ultra Performance Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry.” Biomedical Chromatography, 26, 1325-1332 (2012).
P. Li, W.D. Beck, P.M. Callahan, A.V. Terry and M.G. Bartlett, “Quantitation of Cotinine and its Metabolites by Hydrophilic Interaction Chromatography Tandem Mass Spectrometry.” Journal of Chromatography B, 907, 117-125 (2012).
B. Chen and M.G. Bartlett, “A One Step Solid Phase Extraction Method for the Bioanalysis of a Phosphorothioate Oligonucleotide and its 3’ n-1 Metabolite From Plasma Using UHPLC-MS/MS.” AAPS Journal, 14, 772-780 (2012).
Defective processing of let-7a precursors influences RRM2 expression and chemosensitivity in pancreatic cancer: Role of LIN-28 and SET oncoprotein Bhutia YD, Hung SW, Krentz M, Patel D, Lovin D, Manoharan R, Thomson JR, and Govindarajan R, PLOS ONE (2013) In Press.
J Neurochem. 2012 May;121(4):526-36. doi: 10.1111/j.1471-4159.2012.07694.x. Epub 2012 Mar 21. Glial glutamate transporter and glutamine synthetase regulate GABAergic synaptic strength in the spinal dorsal horn. Jiang E, Yan X, Weng HR.
Bonamassa B, Ma Y, Liu D. Glucocorticoid Receptor-Mediated Transcriptional Regulation of N-acetyltransferase 1 Gene through Distal Promoter. AAPS J. 2012 May 30.
Ma Y, Liu D (2012) Activation of Pregnane X Receptor by Pregnenolone 16 α-carbonitrile Prevents High-Fat Diet-Induced Obesity in AKR/J Mice. PLoS ONE 7(6): e38734. doi:10.1371/journal.pone.0038734
2011
Jia, W., Eneh, J.O., Ratnaparkhe, S., Altman, M.K. and Murph, M.M. MicroRNA-30c-2* expressed in ovarian cancer cells suppresses growth factor induced cellular proliferation and downregulates the oncogene BCL9. Accepted in Molecular Cancer Research. Article in press, epub November 2011.
Kang, J., Cowan, E.A., Oldham, C.D., May, S.W. and Arnold, R.D., The antioxidant phenylaminoethyl selenide reduces doxorubicin-induced cardiotoxicity in a xenograft model of human prostate cancer, Archives of Biochemistry and Biophysics, (2011) 515(1-2) 112-119, epub 8/11, doi:10.1016/j.abb.2011.08.008
Meagan J. McManus, Michael P. Murphy, and James L. Franklin. (2011). The Mitochondria-Targeted Antioxidant MitoQ Prevents Loss of Spatial Memory Retention and Early Neuropathology in a Transgenic Mouse Model of Alzheimer’s Disease. Journal of Neuroscience 31: 15703-15715.
Zhu, G., Alhamhoom, Y., Cummings, B.S. and Arnold, R.D., Synthesis of lipids for development of multifunctional lipid-based drug-carriers, Bioorganic & Medicinal Chemistry Letters, (2011) 21(21) 6370-75, epub 9/2011, doi:10.1016/j.bmcl.2011.08.103 |
Zhang, X., Bull, RJ., Fisher, J., Cotruvo, JA., Cummings, BS. The synergistic effect of sodium chlorite and bromochloroacetic acid on BrO3(-)-induced renal cell death. Toxicology, 2011. Nov 18; 289(2-3): 151-9. Epup 2011 Aug 16.
Aljuffali, I.A., Brainard, B., Moore, J.N., Kwon, S., Allen, D., Robertson, T. and Arnold, R.D., Pharmacokinetic assessment of ketanserin in the horse, Journal of Veterinary Pharmacology and Therapeutics, (in press, 10/11).
AC Capomacchia, ST Garner, JW Beach, US Patent Number 8,034,796, “Glucosamine and glucosamine/anti-inflammatory mutual prodrugs, compositions, and methods”; October 11, 2011
Kenya Kamimura, Takeshi Suda, Guisheng Zhang and Dexi Liu (2011) Advances in Gene Delivery Systems. Pharm. Med. 25:1-14.
Li, J., Yao, Q., and Liu, D. Hydrodynamic cell delivery for simultaneous establishment of tumor growth in mouse lung, liver and kidney. Cancer Biology & Therapy, 2011. 12(8): 737-741.
Mohan N. Thakare, Bridg’ette Israel, Hisham Ahmed, Pamela Garner, Deborah L. Strong, James C. Price, and Anthony C. Capomacchia; ‘Formulation parameters and release mechanism of theophylline loaded ethyl cellulose microspheres: effect of different dual surfactants’; , Pharmaceutical Development and Technology, 2011, 1-7, Early Online, 1083-7450 print/ISSN 1097-9867 online; DOI: 10.3109/10837450.2011.620969
Wang, J; Singh, U.S.; Rawal, R. K.; Chavre S. N.; Sugiyama,M.; Woo,D.; Yoo,J.; Jha, A.K.; Scroggin,M.; Huang,Z.;Murray,M.G.;Govindarajan,R.;Tanaka,Y.;Korba,B.; and Chu, C.K. Antiviral Activity of Novel 2′-Fluoro-6′-methylene-carbocyclic adenosine (FMCA) and its Monophosphate Prodrug (FMCAP) Against Wild-type and Drug-resistant Hepatitis B Virus Mutants,. 2011, Bioorg. Med. Chem. Lttrs., 21, 6328-6331.
Aljuffali, I., Mock, J., Costyn, L.J., Cummings, B.S., Nagy, T. and Arnold, R.D., Enhanced antitumor activity of low-dose continuous administration schedules of Topotecan in prostate cancer, Cancer Biology & Therapy, (2011) 12(5) 407-420, epub 6/11, doi:10.4161/cbt.12.5.15950
Nguyen, D., Nguyen, O., Zhang, H., Prestwich, G.D. and Murph, M.M. (2011). A Bromophosphonate Analogue of Lysophosphatidic Acid Surpasses Dacarbazine in Reducing Cell Proliferation and Viability of MeWo Melanoma Cells. Chapter in “Research on Melanoma - A Glimpse into Current Directions and Future Trends”, Murph, M.M. (Ed.), ISBN: 978-953-307-293-7. InTech. September 2011.
Blum, JL., Kinsey, GR., Monian, P., Sun, B., Cummings, BS., McHowat, J., Schnellmann, RG. Profiling of fatty acids released during calcium-induced mitochondrial permeability transition in isolated rabbit kidney cortex mitochondria. Toxicol in Vitro. 2011 Aug; 25(5): 1001-6. Epup 2011 Apr 3.
Confrite, K., Sundby, M., Mukai, S., J. M. Thomson., Hammond, SM., MacPherson, D. 2011. miR-17-92 cooperates with RB pathway mutations to promote retinoblastoma. Genes Dev. 25(16):1734-45.