Postdoctoral Fellow, Chemical Engineering, California Institute of Technology, Pasadena, CA
Ph.D., Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, WI
B.S., Biomedical Engineering, Marquette University, Milwaukee, WI
Dr. Xiong is interested in biomaterial-based systems in the area of iron chelation therapy, biological metal sensors, and overcoming antibiotic drug resistance in Gram-negative bacteria. Her current research is supported by an NIH R01 grant focusing on the development of materials for chelation of transfusional iron overload.
Visit Dr. Xiong’s lab website at: xionglab.uga.edu.
Liu Z, Lin TM, Purro M, Xiong MP*. Enzymatically biodegradable-polyrotaxane deferoxamine conjugates for iron chelation, ACS Appl Mater & Interfaces, 2016; 8(39) 25788-25797. PMID: 27623539
Zhi Liu, Yan Wang, Max Purro, May P Xiong. “Oxidation-induced degradable nanogels for iron chelation”, Sci Rep, Feb 12;6:20923, 2016. (link)
San Zeng, Arvinder Kapur, Manish Patankar, May P Xiong. “Formulation, characterization, and antitumor properties of trans- and cis-citral in the 4T1 breast cancer xenograft mouse model”, Pharm Res, 32(8) 2548-2558 2015. (link)
Kapur A, Felder M, Fass L, Kaur J, Czarnecki A, Rathi K, Zeng S, Osowski KK, Howell C, Xiong MP, Whelan RJ, Patankar MS*. Modulation of oxidative stress and subsequent induction of apoptosis and endoplasmic reticulum stress allows citral to decrease cancer cell proliferation. Sci Rep, 2016; 6:27530. PMID: 27270209
Yan Wang, Sheng Tu, Dana Steffen, May P Xiong. “Iron complexation to histone deacetylase inhibitors SAHA and LAQ824 in PEGylated liposomes can considerably improve pharmacokinetics in rats”, J Pharm Pharm Sci, 17(4) 583-602, 2014. (link)
Yan Wang, San Zeng, Tien-Min Lin, Lisa Krugner-Higby, Doug Lyman, Dana Steffen, May P Xiong. “Evaluating the anticancer properties of liposomal copper in a nude xenograft mouse model of human prostate cancer: formulation, in vitro, in vivo, histology, and tissue distribution studies”, Pharm Res, 31(11) 3106-3119, 2014. (link)
Yan Wang, Sheng Tu, Anatoly Pinchuck, May P Xiong. “Active drug encapsulation and release kinetics from hydrogel-in-liposome nanoparticles”. J Colloid Interface Sci, 406: 247-255, 2013. (link)
San Zeng, May P Xiong. “Trilayer micelles for combination delivery of rapamycin and siRNA targeting Y-box binding protein-1 (siYB-1)”. Biomaterials, 34(28): 6882-6892, 2013. (link)
Xiong MP, Purro M. Siderophore-polymer conjugates for increasing bacterial sensitivity to antibiotics. Provisional patent No. 62/379121 was filed August 24, 2016 by the Wisconsin Alumni Research Foundation.
Xiong MP, Zhi Liu, Wang Y. Redox responsive compositions and uses thereof. Provisional patent No. 62/061,008 was filed October 7, 2014 by the Wisconsin Alumni Research Foundation.
Xiong MP, Wang Y, Tu S. Liposome-encapsulated hydrogels for use in a drug delivery system. Final patent application published May 8, 2014: US2014/0127287.
Xiong MP, Kwon GS, Bae Y, Kataoka K. Compositions and methods for delivery of therapeutic agents. Final patent application published September 17, 2009: US2009/0232762.