Research Facilities & Equipment

Research Facilities & Equipment

PBS Research Facilities and Equipment:

The College of Pharmacy has approximately 195,000 square feet of research space spanning both the RC Wilson and Pharmacy South buildings. The department provides numerous resources and equipment for research purposes, as well as access to many UGA-wide resources.

Common equipment rooms in the department contain centrifuges (ultracentrifuge and several floor centrifuges), a Guava Flow Cytometer, HPLC systems, Distek dossolution system, Franz cell apparatus, autoclave, dishwasher, ice maker, scintillation counter, two laser fluorescence microscopes with camera-mount for imaging, film developer, gel-image analysis docking station, and a spectrophotometer, among others. Other departmental equipment includes:

  • Roche LightCycler 480II (qRT-PCR)
  • Alpha Innotech Gel Doc Station Fluor Chem Sp
  • Molecular Devices Flexstation 3 (fluorescence, absorbance, fluorescence polarization, time-resolve fluorescence and luminescence in a 96-well format including pipetting) (Roberts)
  • Varian multinuclear 400 MHz and 500 MHz high-field NMR Spectrometers
  • X-ray Diffractometer (Bruker Kappa CCD system mounted on a Nonius FR591 X-ray generator, and accessories)
  • Histology and Microscopy: Olympus X71 light and fluorescent microscope (Beedle)
  • Histology and Microscopy: Microm HM 550 cryostat (Beedle)
  • Beckman 6500 and LS 3801 Liquid Scintillation Counters
  • Spectrophotometer: Nanodrop 2000 (Beedle)
  • Biorad LP Protein Purification System (Roberts)
  • Accusizer 780 Micron and Nicomp 380 Submicron Particle Sizers
  • Biochemistry: Flurchem HD2 imager (Beedle)
  • Biochemistry: BioComp Instruments Gradient Master (Beedle)
  • Differential Scanning Calorimeter
  • New Brunswick I24R (Refrigerated Incubator-Shaker) (Roberts)
  • New Brunswick I26R (Refrigerated Incubator-Shaker) (Roberts)
  • Vankel Dissolution Apparatus
  • Animal Physiology: Accuscan Instruments mouse treadmill (Beedle)
  • Animal Physiology: Accuscan Instruments Versamax Animal Activity Monitor (Beedle)
  • Animal Physiology: Columbus Instruments Grip Strength Meter (Beedle)
  • Fished Scientific 60 Sonic Dismembrator and Alpha Imager
  • Amersham Water Purification System
  • 48-core minisupercomputer with 480 GPU CUDA card for computer simulations (Roberts)
  • Beckman Coulter Ultracentrifuge
  • 23 cu. ft. -80°C Freezer (Roberts)
  • Nikon C-1 Confocal Microscope and Molecular Devices Spectramax M2 Plate Reader

UGA Resources and Equipment:

University of Georgia Bioimaging Research Center (BIRC)

BIRC is a state-of-the-art facility that houses a multi-imaging research suite designed to provide a full range of biological tissue imaging technologies to investigators. Available equipment includes:

  • CTF Omega whole-cortex magnetoencephalography system with 143-channel MEG and 32-channel EEG
  • EGI Geodesic System 200 EleGeneral Electric 16-channel fixed-site Signa HDx 3.0 Tesla Magnetic Resonance Imactroencephalography system with     256-channel head capabilities
  • MRI-simulator, life-size mock-up of the MR magnet complete with stimulus presentation and behavior data acquisition compounding equipment
  • Image processing software including BESA, CURRY, SPM, AFNI, MATLAB, E-Prime, Presentations, and Brain Wave

University of Georgia Electron Microscopy

Located in the College of Veterinary Medicine, faculty and staff have access to a fee-based, full-service facility that houses an electron microscope. This fully-staffed facility is administrated as a service laboratory through the Department of Pathology, but is available to investigators throughout UGA. Equipment includes:

  • JEM 1210 high-resolution transmission electron microscope with film and digital imaging acquisition and archiving
  • JSM 5800 scanning electron microscope with digital image acquisition and thermal film
  • Full range of ancillary equipment including ultra-microptomy, platinum shadowing, plasm coating, critical point drying, and micro ultracentrifugation

University of Georgia Flow Cytometry & FACS Facility

The Center for Tropical and Emerging Global Diseases at UGA provides investigators with a fee-based, state-of-the-art flow cytometry expertise and instrumentation, including:

  • Dako CyAn
  • Becton Dicinson FACS Caliber
  • Bechman Coulter Cytomics FC500
  • Dako MoFlor
  • Fluorescence Activated Cell Sorter
  • Bio-Rad Bio-Plex Protein Array System

University of Georgia Antibody Facility

This facility creates custom antibodies, and includes services such as:

  • The Monoclonal Antibody Project which includes processing three mice (micro-chipping, inoculations, bleeding), serology testing, fusion, hybridoma testing and preservation of the two best cell lines with production and concentration of one liter of cell supernatant per line (if positives can be isolated)
  • The Polyclonal Antibody Project which includes processing five mice (micro-chipping, inoculations, bleeding), serology testing, and terminal bleed for serum from all mice.

University of Georgia Functional Genomics Resources Facility

A part of the Integrated Biotechnology Laboratories (IBL) at UGA, this facility provides a range of fee-based laboratory services for genetics research. This includes:

  • Microarray and genotyping laboratory for gene expression analysis, RNA purification, probe labeling, hybridization, laser scanning, and real-time quantitative PCR.
  • Genotyping services including microsatellite analysis, SNP validation, and AFLP analysis
  • ScanArray 5000 equipped with an external blue laser
  • Applied Biosciences 377 Sequencer
  • Applied Biosystems 7900 Sequence Detection System
  • Real-time PCR services on ABI 7900 Sequence Detector, equipped with low-density array block; microplate format blocks are also available for gene expression studies or to validate microarray data

University of Georgia Sequencing and Synthesis Facility

This core facility is capable of sequencing single-stranded DNA, double-stranded DNA, or PCR products on automated DNA sequencers. Data is provided as a color printout, as a text-file in GCG format, and as a raw-data file for downloading. Turnaround time is three to five working days. DNA sequencing is offered in-house; Peptide synthesis is outsourced to Sigma/Genosys.

University of Georgia Instrument Shop

The Instrument Shop builds one-of-a-kind research instruments, laboratory devices, teaching aids, replacement parts for obsolete equipment, and modifies existing equipment. They house a staff of eight and a full complement of machine tools, welding and sheet metal fabrication equipment. In addition, CNC milling and turning used with computer-aided design and manufacturing (CAD/CAM) allow the capability to make one or many items.